Fig. 1 · Structure

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(R)-PHA533533

Inactive Enantiomer

(R)-PHA533533 is the inactive enantiomer of (S)-PHA533533, which acts as a cyclin-dependent kinase 2 (CDK2) inhibitor with identified antitumor activity. This compound serves as a necessary control in biochemical assays aimed at studying the specific effects of the active enantiomer on cell proliferation and cancer progression. Research utilizing (R)-PHA533533 can provide insights into the stereospecificity and selectivity of CDK2 inhibitors in cancer therapy.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 437982-90-6
Applications Inactive Enantiomer
Formula C19H22N4O2
Molecular Weight 338.40
SMILES
C[C@H](C1=CC=C(N2C(CCC2)=O)C=C1)C(NC3=NNC(C4CC4)=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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