Fig. 1 · Structure
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(R)-Praziquantel-d11
Antischistosomal Agent
(R)-Praziquantel-d11 is a deuterium-labeled derivative of (R)-Praziquantel, the active enantiomer exhibiting selective agonistic activity at the 5-HT2B receptor. This compound serves as an effective antischistosomal agent, targeting the lifecycle stages of schistosomes to disrupt their development and survival. Research applications include studying the pharmacodynamics and metabolic pathways of (R)-Praziquantel and evaluating its efficacy in schistosomiasis models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1399880-38-6 |
| Applications | Antischistosomal Agent |
| Formula | C19H13D11N2O2 |
| Molecular Weight | 323.47 |
| SMILES | O=C1CN(C(C2([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C2([2H])[2H])=O)C[C@]3([H])N1CCC4=C3C=CC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.