Fig. 1 · Structure
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(R,R)-ART0380
Enantiomer of ART0380
(R,R)-ART0380 is the enantiomer of ART0380 and functions as a potent and selective inhibitor of ATR (Ataxia Telangiectasia and Rad3 related protein). This compound exhibits significant anti-tumor activity and is ideal for research applications focused on advanced or metastatic solid tumors. Its selective inhibition makes it a valuable tool for exploring novel therapeutic strategies in cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2267316-75-4 |
| Applications | Enantiomer of ART0380 |
| Formula | C18H24N6O2S |
| Molecular Weight | 388.49 |
| SMILES | C[C@@H]1COCCN1C2=NC(C3=CC=NC(N)=C3)=NC(N=[S@@](C)(C4CC4)=O)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.