Fig. 1 · Structure
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(R,R)-Palonosetron Hydrochloride
5-HT Receptor
(R,R)-Palonosetron Hydrochloride is a selective antagonist of the 5-HT3 receptor. This compound exhibits significant antiemetic properties, making it valuable in the prevention of chemotherapy-induced nausea and vomiting. Its high affinity for the 5-HT3 receptor can also facilitate research on serotonin signaling pathways and their role in gastrointestinal function and neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 135729-75-8 |
| Applications | 5-HT Receptor |
| Formula | C19H25ClN2O |
| Molecular Weight | 332.87 |
| SMILES | O=C1N(C[C@]([H])(CCC2)C3=C2C=CC=C13)[C@H]4CN5CCC4CC5.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.