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(R,R,S)-AHPC

Ligand for E3 Ligase

(R,R,S)-AHPC is a ligand for the E3 ligase von Hippel-Lindau (VHL). This compound is designed to recruit the VHL protein, facilitating the degradation of target proteins through the formation of PROTACs (Proteolysis Targeting Chimeras). By linking (R,R,S)-AHPC to specific target protein ligands, researchers can effectively study protein regulation and explore novel therapeutic strategies in cellular pathways.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2764746-08-7
Applications	Ligand for E3 Ligase
Formula	C₂₂H₃₁ClN₄O₃S
Molecular Weight	467.02
Synonyms	(R,R,S)-VH032-NH2; (R,R,S)-VHL ligand 1
SMILES	CC1=C(SC=N1)C(C=C2)=CC=C2CNC([C@@H]3N(C[C@@H](C3)O)C([C@@H](N)C(C)(C)C)=O)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.