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(R)-RS 56812

5-HT3 receptor antagonist

(R)-RS 56812 is a selective antagonist of the 5-HT3 receptor. This compound has been shown to enhance cognitive performance in primate models, particularly in tasks involving delayed matching. The (R) isomer exhibits greater efficacy in facilitating cognitive function compared to its (S) counterpart, suggesting potential therapeutic applications in conditions associated with cognitive decline.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	143137-37-5
Applications	5-HT3 receptor antagonist
Formula	C₁₈H₂₁N₃O₂
Molecular Weight	311.38
SMILES	[H]C1(CCN(CC1)C2)[C@H]2NC(C(C3=CN(C)C4=CC=CC=C34)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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(R)-RS 56812

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(R)-RS 56812 1 mg