Fig. 1 · Structure

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(R,S,R)-AHPC-NHBoc

Ligand for E3 Ligase

(R,S,R)-AHPC-NHBoc is a ligand for the E3 ubiquitin ligase VHL that facilitates the recruitment of the VHL protein. This compound can be utilized to construct PROTACs by linking it to a target protein ligand through a suitable linker. Its ability to modulate protein degradation pathways makes it a valuable tool for research in targeted protein degradation and related therapeutic applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 1799506-31-2
Applications Ligand for E3 Ligase
Formula C27H38N4O5S
Molecular Weight 530.68
SMILES
C([C@H](NC(OC(C)(C)C)=O)[C@](C)(C)C)(=O)N1[C@@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@H](O)C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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