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(R,S,S)-VH032-Me TFA

E3 Ligase Ligand

(R,S,S)-VH032-Me TFA is a selective E3 ligase ligand that serves as a crucial tool for the development of targeted protein degradation strategies. This compound is utilized in the synthesis of dTAGV-1 hydrochloride, facilitating research into ubiquitin-proteasome system modulation and its implications in cancer and cellular biology. Its ability to modulate E3 ligase activity makes it valuable for investigating innovative therapeutic approaches in biomedical research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2451573-93-4
Applications	E3 Ligase Ligand
Formula	C₂₅H₃₃F₃N₄O₅S
Molecular Weight	558.61
SMILES	N[C@@H](C(C)(C)C)C(N1[C@@H](C(N[C@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C)=O)C[C@H](O)C1)=O.OC(C(F)(F)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.