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(R,S,S)-VH032-Me
Ligands for E3 Ligase
(R,S,S)-VH032-Me is a ligand for E3 ubiquitin ligase, playing a crucial role in targeted protein degradation through the ubiquitin-proteasome pathway. It can be conjugated to proteins via a linker to create PROTACs such as dTAGV-1-NEG, which facilitate the selective degradation of oncogenic proteins. This compound is essential for studies involving targeted protein degradation, offering valuable insights into cancer biology and therapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 1948273-05-9 |
| Applications | Ligands for E3 Ligase |
| Formula | C23H32N4O3S |
| Molecular Weight | 444.59 |
| SMILES | N[C@H](C(N1[C@H](C[C@@H](C1)O)C(N[C@@H](C)C2=CC=C(C=C2)C3=C(N=CS3)C)=O)=O)C(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.