Fig. 1 · Structure

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(R)-SARM1-IN-5

(R)-enantiomer of SARM1-IN-5

(R)-SARM1-IN-5 is the (R)-enantiomer of a selective SARM1 inhibitor. This compound plays a crucial role in modulating axonal degeneration, making it applicable in research focused on neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS). Its inhibition of SARM1 offers valuable insights into potential therapeutic strategies for these conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2762081-31-0
Applications (R)-enantiomer of SARM1-IN-5
Formula C18H17FN6O
Molecular Weight 352.37
SMILES
O=C1[C@H](CCCN1C2=NN=C(N2)C3=CC=NC=C3)CC4=CC=C(N=C4)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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