Fig. 1 · Structure
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(R)-SCH 42495
Neutral Endopeptidase Inhibitor
(R)-SCH 42495 is a selective inhibitor of neutral endopeptidase (NEP), exhibiting antihypertensive properties. It serves as the less active enantiomer of SCH 42495, an orally bioavailable prodrug that is converted to the active form SCH 42354. This compound is valuable in research related to cardiovascular regulation and peptide metabolism, facilitating studies on blood pressure modulation and the role of NEP in various biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 156792-25-5 |
| Applications | Neutral Endopeptidase Inhibitor |
| Formula | C20H29NO4S2 |
| Molecular Weight | 411.58 |
| SMILES | CSCC[C@@H](C(OCC)=O)NC([C@H](CSC(C)=O)CC1=CC=CC=C1C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.