Fig. 1 · Structure
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(R)-SKF 38393 hydrochloride
D1 Dopamine Receptor Antagonist
(R)-SKF 38393 hydrochloride is a potent and selective antagonist of the D1 dopamine receptor. This compound effectively inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels, making it a valuable tool for exploring dopamine signaling pathways. It is commonly used in research applications focused on neuropharmacology and the modulation of dopaminergic systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 81702-42-3 |
| Applications | D1 Dopamine Receptor Antagonist |
| Formula | C16H18ClNO2 |
| Molecular Weight | 291.77 |
| Synonyms | (±)-SKF-38393 hydrochloride; SKF-38393A hydrochloride |
| SMILES | OC1=C(C=C2[C@H](CNCCC2=C1)C3=CC=CC=C3)O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.