Fig. 1 · Structure
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(R)-Sortilin antagonist 1
Sortilin Antagonist
(R)-Sortilin antagonist 1 is a selective antagonist of sortilin, designed to inhibit the sortilin-mediated apoptosis pathway by disrupting its interaction with the ligand pro-neurotrophin. This compound is valuable for investigating the role of sortilin in apoptosis and is particularly relevant in studies related to hearing loss. Its unique mechanism makes it a useful tool for elucidating the biological functions of sortilin in various research contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2889422-86-8 |
| Applications | Sortilin Antagonist |
| Formula | C20H24N2O4 |
| Molecular Weight | 356.42 |
| SMILES | CC(C)(C)CC[C@H](C(O)=O)NC(C(C=N1)=CC=C1OC2=CC=CC=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.