Fig. 1 · Structure

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(R)-VX-984

(R)-enantiomer of VX-984

(R)-VX-984 is the (R)-enantiomer of VX-984, a potent inhibitor of DNA-dependent protein kinase (DNA-PK). This compound effectively impairs DNA repair mechanisms, making it a valuable tool for elucidating the role of DNA-PK in cellular processes. Its inhibitory action positions (R)-VX-984 as a significant reagent for research in cancer biology and therapeutic interventions targeting DNA repair pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2448475-19-0
Applications (R)-enantiomer of VX-984
Formula C23H21D2N7O
Molecular Weight 415.49
Synonyms (R)-M9831
SMILES
O=C(C1=CC=NC2=C([C@@H](C)CNC3=CC(C4=C([2H])N=C(C)N=C4[2H])=NC=N3)C=CC=C12)NC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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