R214127 is a selective antagonist of the mGlu1 receptor, exhibiting IC50 values of 6 nM for rat mGlu1a and 14 nM for human mGlu1a. This compound engages a site within the glutamate binding pocket, competing for the same transmembrane segment VII as other noncompetitive mGlu1 antagonists. R214127 is utilized in research applications focusing on neuromodulation and the elucidation of mGlu1 receptor functions in various physiological and pathological contexts.
R214127 is a selective antagonist of the mGlu1 receptor, exhibiting IC50 values of 6 nM for rat mGlu1a and 14 nM for human mGlu1a. This compound engages a site within the glutamate binding pocket, competing for the same transmembrane segment VII as other noncompetitive mGlu1 antagonists. R214127 is utilized in research applications focusing on neuromodulation and the elucidation of mGlu1 receptor functions in various physiological and pathological contexts.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
