R428

Catalog No.: A13741

Axl Inhibitor

R428

R428 Chemical Structure

CAS NO. 1037624-75-1

R428 is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer.

Availability: In stock

Package Price Qty
2 mg

Regular Price: $80.00

Special Price $72.00

5 mg

Regular Price: $150.00

Special Price $135.00

10 mg

Regular Price: $250.00

Special Price $225.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

R428 is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer.
Targets
Axl
14 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.69 mL 197.38 mL
0.5 mM 3.95 mL 19.74 mL 39.48 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13741
Actions Inhibitor
M. Wt 506.64
Formula C30H34N8
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1037624-75-1
Synonyms BGB324, BGB 324, BGB-324, R-428
SMILES C1CCN(C1)[[email protected]]2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76

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