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RA183

Ligands for E3 Ligase

RA183 is a selective ligand for E3 ligases, facilitating the development of proteolysis-targeting chimeras (PROTACs). This compound enables the targeted degradation of specific proteins by harnessing the ubiquitin-proteasome system, making it a valuable tool in chemical biology and drug discovery. RA183 can be utilized in various research applications aimed at elucidating protein function and developing innovative therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2649154-64-1
Applications	Ligands for E3 Ligase
Formula	C₂₈H₂₄N₄O₆
Molecular Weight	512.51
SMILES	N[C@H](C(N1C/C(C(/C(C1)=C/C2=CC=C([N+]([O-])=O)C=C2)=O)=C\C3=CC=C([N+]([O-])=O)C=C3)=O)CC4=CC=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.