Fig. 1 · Structure
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Rabeximod
Anti-rheumatic Compound
Rabeximod is an anti-rheumatic compound that primarily targets Toll-like receptors 2 and 4 (TLR2 and TLR4). It impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages, making it a valuable tool for studying rheumatoid arthritis (RA). Rabeximod is applicable in preclinical research focused on the modulation of innate immune responses in the context of autoimmune diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 872178-65-9 |
| Applications | Anti-rheumatic Compound |
| Formula | C22H24ClN5O |
| Molecular Weight | 409.91 |
| Synonyms | ROB-803 |
| SMILES | O=C(CN1C2=NC3=C(N=C2C4=C1C=CC(Cl)=C4)C=C(C)C(C)=C3)NCCN(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.