(Rac)-3′-Hydroxy simvastatin is a drug metabolite derived from Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase. With a Ki value of 0.2 nM, it plays a crucial role in cholesterol biosynthesis regulation. This compound is relevant in pharmacokinetic studies and investigations into the metabolic pathways of statins.
(Rac)-3′-Hydroxy simvastatin is a drug metabolite derived from Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase. With a Ki value of 0.2 nM, it plays a crucial role in cholesterol biosynthesis regulation. This compound is relevant in pharmacokinetic studies and investigations into the metabolic pathways of statins.
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