(Rac)-3′-Hydroxy simvastatin

Catalog No.: A70313
Drug Metabolite
(Rac)-3′-Hydroxy simvastatin is a drug metabolite derived from Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase. With a Ki value of 0.2 nM, it plays a crucial role in cholesterol biosynthesis regulation. This compound is relevant in pharmacokinetic studies and investigations into the metabolic pathways of statins.
Grouped product items
Size Price Stock Qty
1mg
$345.00
In stock
2.5mg
$785.00
In stock
25mg
$1,405.00
In stock
50mg
$1,790.00
In stock
100mg
$2,240.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(Rac)-3′-Hydroxy simvastatin is a drug metabolite derived from Simvastatin, which acts as a competitive inhibitor of HMG-CoA reductase. With a Ki value of 0.2 nM, it plays a crucial role in cholesterol biosynthesis regulation. This compound is relevant in pharmacokinetic studies and investigations into the metabolic pathways of statins.
Product Information
Catalog NumA70313
FormulaC25H38O6
Molecular Weight434.57
CAS Number126313-98-2
SMILESCC(O)C(C)(C)C(OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(O3)=O)C12)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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