Fig. 1 · Structure
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(rac)-AL-37350A
5-HT Receptor Agonist
(rac)-AL-37350A is a potent agonist of the 5-HT2 receptor, known for its ability to lower intraocular pressure. With a high affinity and selectivity for this receptor, (rac)-AL-37350A demonstrates significant efficacy in reducing intraocular pressure in conscious hypertensive cynomolgus monkeys. This compound is valuable for research applications exploring glaucoma treatments and the physiological mechanisms of 5-HT receptor activation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 362603-40-5 |
| Applications | 5-HT Receptor Agonist |
| Formula | C14H18N2O |
| Molecular Weight | 230.31 |
| Synonyms | (rac)-4,5-DHP-AMT |
| SMILES | NC(C)CC1=CNC2=C1C(CCCO3)=C3C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.