Fig. 1 · Structure
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(Rac)-Apremilast-d5
Deuterated (R)-Apremilast
(Rac)-Apremilast-d5 is a deuterated form of (R)-Apremilast, designed for use in various scientific applications. This compound selectively inhibits phosphodiesterase 4 (PDE4), leading to increased intracellular levels of cyclic AMP, which modulates inflammatory responses. It is primarily utilized in research related to autoimmune diseases and inflammation, making it a valuable tool for studying drug mechanisms and efficacy in various biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1258597-61-3 |
| Applications | Deuterated (R)-Apremilast |
| Formula | C22H19D5N2O7S |
| Molecular Weight | 465.53 |
| Synonyms | (Rac)-CC-10004 d5 |
| SMILES | CC(NC1=CC=CC(C(N2C(C3=CC=C(OC)C(OC([2H])([2H])C([2H])([2H])[2H])=C3)CS(=O)(C)=O)=O)=C1C2=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.