Fig. 1 · Structure
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(Rac)-Chem-0199
Racemic Mixture of Chem-0199
(Rac)-Chem-0199 is the racemic mixture of Chem-0199, an inhibitor of Adipocyte Enhancer-Binding Protein 1 (AEBP1). This compound disrupts the interaction between AEBP1 and CKAP4, which enhances antitumor immunity. Additionally, (Rac)-Chem-0199 inhibits Akt phosphorylation (p-Akt) and downregulates PD-L1 expression. It is applicable in cancer research, particularly in studies related to colon cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 122981-77-5 |
| Applications | Racemic Mixture of Chem-0199 |
| Formula | C13H18N2O2 |
| Molecular Weight | 234.29 |
| SMILES | CC1(C)N(O)C(C2=CC=CC=C2)[N+]([O-])=C1CC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.