Fig. 1 · Structure

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(rac)-dWIZ-1

Wiz Inhibitor

(rac)-dWIZ-1 is a potent WIZ inhibitor, with a DC50 value of 0.36 μM. This compound is useful in research related to inherited blood disorders, particularly hemoglobinopathies such as sickle cell disease and beta-thalassemia. Its selective inhibition of WIZ may provide insights into therapeutic strategies for managing these conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2879251-63-3
Applications Wiz Inhibitor
Formula C22H29N3O4
Molecular Weight 399.48
SMILES
O=C1C2=CC=C(C=C2CN1C3C(NC(CC3)=O)=O)OC(C4N(CCCC4)CC)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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