Fig. 1 · Structure
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(Rac)-EC5026
sEH Inhibitor
(Rac)-EC5026 is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) with a Ki of 0.06 nM. This compound demonstrates significant biological activity relevant to neurological disorders, making it a valuable tool for investigating the pathophysiology of Parkinson's disease and dementia with Lewy Bodies (DLB). Researchers can utilize (Rac)-EC5026 to explore therapeutic strategies targeting sEH in the context of these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1809885-55-9 |
| Applications | sEH Inhibitor |
| Formula | C18H23F4N3O3 |
| Molecular Weight | 405.39 |
| Synonyms | (Rac)-BPN-19186 |
| SMILES | O=C(NC1CCN(C(C(C)CC)=O)CC1)NC2=CC=C(OC(F)(F)F)C(F)=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.