Fig. 1 · Structure
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(Rac)-Etavopivat
Cat. No.
A77414
CAS
2622070-93-1
PKR Activator
(Rac)-Etavopivat is an isomer of Etavopivat and functions as an activator of erythrocyte pyruvate kinase-R (PKR). This compound exhibits the potential to enhance glycolytic flux in erythrocytes, making it valuable for research on sickle cell disease and other hemoglobinopathies. Its oral bioavailability allows for convenient dosing in in vitro and in vivo studies, supporting investigations into erythrocyte metabolism and therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2622070-93-1 |
| Applications | PKR Activator |
| Formula | C22H23N3O6S |
| Molecular Weight | 457.50 |
| Synonyms | (Rac)-FT-4202 |
| SMILES | O=C(C(CO)C1=CC=CC=C1)N2CC3=C(CN(S(=O)(C4=CN=C5OCCOC5=C4)=O)C3)C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.