Fig. 1 · Structure
Documents & Downloads
(rac)-Exatecan Intermediate 1
ADC Toxin
(rac)-Exatecan Intermediate 1 is an isomer of Exatecan Intermediate 1, serving as a crucial precursor for the synthesis of Exatecan, a camptothecin analog that targets DNA. This compound exhibits significant anticancer activity by inhibiting DNA replication and disrupting the proliferation of tumor cells. It is primarily utilized in research focused on various cancers, including ovarian, lung, and breast cancer, making it an essential reagent in the development of antibody-drug conjugates (ADCs) for targeted cancer therapies.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 102978-40-5 |
| Applications | ADC Toxin |
| Formula | C13H13NO5 |
| Molecular Weight | 263.25 |
| SMILES | O=C1C(O)(CC)C(C=C23)=C(CO1)C(N3CCC2=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.