(Rac)-GSK866

Catalog No.: A64812
GR Ligand
(Rac)-GSK866 is a non-steroidal ligand that targets the glucocorticoid receptor (GR). This compound serves as an important tool for investigating GR functionality by providing insights into ligand binding mechanisms. The crystal structure of (Rac)-GSK866 in complex with the GR ligand-binding domain (PDB: 3E7C) can facilitate the exploration of GR-targeted therapeutic strategies and the development of novel GR modulators.
Grouped product items
Size Price Stock Qty
25mg
$2,160.00
In stock
50mg
$2,770.00
In stock
100mg
$3,680.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(Rac)-GSK866 is a non-steroidal ligand that targets the glucocorticoid receptor (GR). This compound serves as an important tool for investigating GR functionality by providing insights into ligand binding mechanisms. The crystal structure of (Rac)-GSK866 in complex with the GR ligand-binding domain (PDB: 3E7C) can facilitate the exploration of GR-targeted therapeutic strategies and the development of novel GR modulators.
Product Information
Catalog NumA64812
FormulaC23H21Cl2F4N5O3
Molecular Weight562.34
CAS Number960248-81-1
SMILESO=C(C1=C(N)N(C2=CC=C(C=C2)F)N=C1)NCC(CN(CC)C(C3=C(Cl)C=CC=C3Cl)=O)(C(F)(F)F)O
SynonymsGSK47866A
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