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(rac)-K20

Racemate

(rac)-K20 is the racemic mixture of K20, a selective inhibitor of KRas G12C with an IC50 value of 1.16 µM. This compound exhibits notable antitumor activity, making it a valuable tool for cancer research. It is primarily utilized in studies involving KRas G12C mutations and their role in oncogenesis.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2915618-92-5
Applications	Racemate
Formula	C₂₄H₂₀Cl₂F₄N₄O₂
Molecular Weight	543.34
SMILES	C=C(C(N1CCN(C(C1)C)C2=NC=NC3=C(C(C4=CC(Cl)=CC=C4OC)=C(C=C23)Cl)F)=O)C(F)(F)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.