Fig. 1 · Structure
Documents & Downloads
(rac)-Lomedeucitinib
Racemate
(rac)-Lomedeucitinib is a racemic mixture that functions primarily as a selective inhibitor of the tyrosine protein kinase 2 (TYK2). This compound exhibits potent anti-inflammatory effects, specifically inhibiting interferon-alpha production with an IC50 value of 0.047 μM, thereby modulating immune responses. Its biological activity makes it suitable for research applications related to plaque psoriasis and pruritus, facilitating investigations into therapeutic interventions for these conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2328064-33-9 |
| Applications | Racemate |
| Formula | C18H17D3N6O4S |
| Molecular Weight | 419.47 |
| Synonyms | (rac)-BMS-986322 |
| SMILES | O=C(C1=NN=C(NC(C2CC23CC3)=O)C=C1NC4=NC=CC=C4S(=O)(C)=O)NC([2H])([2H])[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.