Fig. 1 · Structure
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(Rac)-NMDAR antagonist 1
iGluR Antagonist
(Rac)-NMDAR antagonist 1 is a racemic mixture that selectively inhibits the NR2B subunit of the N-methyl-D-aspartate receptor (NMDAR). This compound demonstrates potent antagonistic activity, making it valuable for studies involving excitatory neurotransmission and neuroprotection. Its oral bioavailability additionally supports its use in in vivo research applications aimed at elucidating the role of NMDAR in various neurological conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2435557-99-4 |
| Applications | iGluR Antagonist |
| Formula | C20H20BrN3O2 |
| Molecular Weight | 414.30 |
| SMILES | O=C(NCCC1=CC=C(O)C=C1)C2CCC3=NC4=CC=C(Br)C=C4CN32 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.