Fig. 1 · Structure
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(Rac)-PF-06256142
D1 Receptor
(Rac)-PF-06256142 is an agonist of the D1 receptor, exhibiting an EC50 of 107 nM. This compound plays a significant role in the study of dopaminergic signaling pathways and is relevant for research applications focused on psychiatric disorders such as schizophrenia and neurodegenerative conditions like Parkinson's disease. Its biological activity provides a useful tool for exploring the therapeutic potential of D1 receptor modulation in these diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1609580-97-3 |
| Applications | D1 Receptor |
| Formula | C21H16N4O2 |
| Molecular Weight | 356.38 |
| SMILES | CC1=C(C2=C(C)N=CC3=NC=CN32)C=CC(OC4=C(C=CO5)C5=CC=N4)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.