Fig. 1 · Structure
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(rac)-Poriol
Antioxidant Agent
(rac)-Poriol, also known as 5,7,4'-Trihydroxy-6-methylflavanone, functions as an antioxidant agent through its ability to scavenge free radicals, evidenced by an IC50 of 0.18 µg/mL against DPPH. It demonstrates significant anti-inflammatory activity by inhibiting lipopolysaccharide-induced nitric oxide generation in RAW264.7 cells, achieving a 98.35% inhibition rate at 10 μM. Additionally, (rac)-Poriol exhibits strong binding affinity for key inflammatory mediators, including iNOS, COX-1, COX-2, TNF-α, and IL-1β, making it a valuable tool for research in oxidative stress and inflammation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 70460-58-1 |
| Applications | Antioxidant Agent |
| Formula | C16H14O5 |
| Molecular Weight | 286.28 |
| Synonyms | 5,7,4'-Trihydroxy-6-methylflavanone |
| SMILES | O=C1C2=C(C(C)=C(C=C2OC(C1)C3=CC=C(C=C3)O)O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.