(Rac)-Ruxolitinib-d9

Catalog No.: A33271
Stable Isotope
(Rac)-Ruxolitinib-d9 is a deuterated form of (Rac)-Ruxolitinib, a selective inhibitor of the Janus kinase 2 (JAK2) enzyme. This stable isotope-labeled compound is essential for elucidating the pharmacokinetics and metabolism of (Rac)-Ruxolitinib in biological systems. It is particularly useful in quantitative mass spectrometry applications and metabolic studies, aiding in the understanding of JAK2-related signaling pathways in various diseases, including hematological disorders.
Grouped product items
Size Price Stock Qty
1mg
$335.00
In stock
Bulk Size
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(Rac)-Ruxolitinib-d9 is a deuterated form of (Rac)-Ruxolitinib, a selective inhibitor of the Janus kinase 2 (JAK2) enzyme. This stable isotope-labeled compound is essential for elucidating the pharmacokinetics and metabolism of (Rac)-Ruxolitinib in biological systems. It is particularly useful in quantitative mass spectrometry applications and metabolic studies, aiding in the understanding of JAK2-related signaling pathways in various diseases, including hematological disorders.
Product Information
Catalog NumA33271
FormulaC17H9D9N6
Molecular Weight315.42
CAS Number2469553-67-9
SMILESN#CCC(C1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H])N2C=C(C=N2)C3=C4C(NC=C4)=NC=N3
Synonyms(Rac)-INCB18424-d9; Ruxotinib racemate-d9
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