Fig. 1 · Structure
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(Rac)-Saphenamycin
gp41 Inhibitor
(Rac)-Saphenamycin is a potent inhibitor of the gp41 membrane fusion protein essential for HIV-1 entry into host cells. It demonstrates significant antiviral activity through its ability to engage in pi-pi interactions with tryptophan residue 571, interfering with viral fusion processes. This compound is valuable for research in HIV-1 pathogenesis and therapeutic development targeting viral entry mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 634600-55-8 |
| Applications | gp41 Inhibitor |
| Formula | C23H18N2O5 |
| Molecular Weight | 402.40 |
| SMILES | O=C(C1=CC=CC2=NC3=C(C(OC(C4=C(C)C=CC=C4O)=O)C)C=CC=C3N=C21)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.