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(Rac)-Sezolamide hydrochloride

Carbonic Anhydrase Inhibitor

(Rac)-Sezolamide hydrochloride is a potent inhibitor of carbonic anhydrase, with a Ki value of 12.0 nM. This compound effectively lowers intraocular pressure (IOP), making it valuable for research into glaucoma and related ocular conditions. Its mechanism of action provides a useful tool for investigating the physiological and pharmacological pathways involved in eye health and disease.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	126453-94-9
Applications	Carbonic Anhydrase Inhibitor
Formula	C₁₁H₁₉ClN₂O₄S₃
Molecular Weight	374.93
Synonyms	MK-927; (Rac)-MK 417
SMILES	O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.