Fig. 1 · Structure
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(Rac)-Sezolamide
Carbonic Anhydrase Inhibitor
(Rac)-Sezolamide is a potent carbonic anhydrase inhibitor (CAI) with a Ki value of 12.0 nM. It exhibits significant topical intraocular pressure (IOP) lowering effects, making it a valuable tool in the study of glaucoma and related ocular conditions. Researchers can utilize (Rac)-Sezolamide to explore pathways involved in IOP regulation and to develop therapeutic strategies for managing glaucoma.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 123291-07-6 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C11H18N2O4S3 |
| Molecular Weight | 338.47 |
| Synonyms | MK-927 free base; (Rac)-MK 417 free base |
| SMILES | O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.