Documents & Downloads

(Rac)-Sitagliptin-d4

Stable Isotope

(Rac)-Sitagliptin-d4 is a deuterium-labeled isoform of Sitagliptin, specifically designed as a stable isotope for research applications. As a potent orally active inhibitor of dipeptidyl peptidase IV (DPP4), it exhibits an IC50 of 19 nM in Caco-2 cell extracts. This compound is invaluable for studies involving glucose metabolism, diabetes treatment mechanisms, and metabolic signaling pathways. Its use in isotopic labeling enhances the accuracy of biochemical assays and metabolic studies.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
CAS Number	1620233-72-8
Applications	Stable Isotope
Formula	C₁₆H₁₁D₄F₆N₅O
Molecular Weight	411.34
Synonyms	(Rac)-MK-0431-d4
SMILES	FC(F)(C1=NN=C2N1C([2H])([2H])C([2H])([2H])N(C(CC(N)CC3=C(C=C(C(F)=C3)F)F)=O)C2)F

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.