Fig. 1 · Structure
Documents & Downloads
(Rac)-Tezacaftor
Tezacaftor Racemate
(Rac)-Tezacaftor is a racemic mixture of Tezacaftor, a known F508del CFTR corrector. This compound is primarily utilized in research related to cystic fibrosis, where it enhances the function of the CFTR protein to improve chloride transport in epithelial cells. Its ability to correct the folding and trafficking of the F508del mutation makes it an important tool in the study of therapeutic strategies for treating cystic fibrosis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1226709-85-8 |
| Applications | Tezacaftor Racemate |
| Formula | C26H27F3N2O6 |
| Molecular Weight | 520.50 |
| Synonyms | (Rac)-VX-661 |
| SMILES | FC1=C(NC(C2(CC2)C3=CC4=C(OC(F)(F)O4)C=C3)=O)C=C(C=C5C(C)(C)CO)C(N5CC(O)CO)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.