Fig. 1 · Structure

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(Rac)-UCB-J

SV2A Ligand

(Rac)-UCB-J is a selective ligand for synaptic vesicle protein 2A (SV2A), exhibiting a pIC50 value of 8.2. This compound serves as a valuable PET tracer for SV2A, facilitating research in the diagnosis and understanding of epilepsy. Its application in neuroimaging studies enhances insights into synaptic function and potential therapeutic targets for neurological disorders.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 1604786-87-9
Applications SV2A Ligand
Formula C17H15F3N2O
Molecular Weight 320.31
SMILES
O=C1CC(C2=CC(F)=C(C(F)=C2)F)CN1CC3=CC=NC=C3C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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