Fig. 1 · Structure

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Radafaxine

Antidepressant Compound

Radafaxine, a selective dopamine transporter (DAT) blocker, serves as an active metabolite of Bupropion and functions as an antidepressant. Its primary mechanism involves the inhibition of dopamine reuptake, which enhances dopaminergic neurotransmission. Radafaxine is primarily utilized in research focused on mood disorders and the neurobiological underpinnings of depression.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 192374-14-4
Applications Antidepressant Compound
Formula C13H18ClNO2
Molecular Weight 255.74
Synonyms (S,S)-Hydroxybupropion; GW-353162A free base; BW-306U free base
SMILES
O[C@]1(C2=CC=CC(Cl)=C2)[C@H](C)NC(C)(C)CO1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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