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Radalbuvir

NS5B RdRp Inhibitor

Radalbuvir is a non-nucleoside inhibitor targeting nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). It demonstrates potent antiviral activity against hepatitis C virus (HCV), with intrinsic EC50 values of 2.9 nM for genotype 1a and 6 nM for genotype 1b. This compound is primarily utilized in research focused on understanding HCV replication mechanisms and developing effective antiviral therapies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1314795-11-3
Applications	NS5B RdRp Inhibitor
Formula	C₃₀H₄₁NO₆S
Molecular Weight	543.71
Synonyms	GS-9669
SMILES	O=C([C@@H]1CCC(C)=CC1)N([C@H]2CC[C@@](CO[C@H]3CCOC3)(O)CC2)C(C=C(C#CC(C)(C)C)S4)=C4C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.