Fig. 1 · Structure
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Rafabegron
β3-adrenoceptor Agonist
Rafabegron is a selective β3-adrenoceptor agonist known for its role in metabolic regulation. It has demonstrated the ability to decrease blood glucose, insulin, free fatty acids, and triglyceride levels in diabetic and obese mouse models. This compound is valuable for research applications focused on obesity, diabetes, and metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 244081-42-3 |
| Applications | β3-adrenoceptor Agonist |
| Formula | C21H23ClN2O4 |
| Molecular Weight | 402.87 |
| Synonyms | AJ‐9677 |
| SMILES | OC(COC1=C2C(C(C[C@@H](C)NC[C@@H](C3=CC(Cl)=CC=C3)O)=CN2)=CC=C1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.