Fig. 1 · Structure
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Ralmitaront
TAAR1 Agonist
Ralmitaront is an orally active agonist of trace amine-associated receptor 1 (TAAR1) with an EC50 of 110.4 nM. It exhibits antipsychotic, cognitive enhancement, and antidepressant effects in rodent models. Ralmitaront is valuable for investigating neuropsychiatric disorders, including schizophrenia and schizoaffective disorder, providing insights into potential therapeutic mechanisms and efficacy in neurosuppressant applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 2133417-13-5 |
| Applications | TAAR1 Agonist |
| Formula | C17H22N4O2 |
| Molecular Weight | 314.38 |
| Synonyms | RO6889450 |
| SMILES | O=C(C1=NNC(CC)=C1C)NC2=CC=C([C@H]3CNCCO3)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.