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Ramipril-d4

Stable Isotope

Ramipril-d4 is a deuterated form of Ramipril, an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 5 nM. This stable isotope is utilized in pharmacokinetic studies and metabolic research to track drug metabolism and distribution. Ramipril-d4 serves as a valuable tool in understanding the pharmacodynamics and therapeutic effects of ACE inhibitors in cardiovascular research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1132661-83-6
Applications	Stable Isotope
Formula	C₂₃H₂₈D₄N₂O₅
Molecular Weight	420.54
Synonyms	HOE-498-d4
SMILES	CCOC([C@H](CCC1=CC=CC=C1)N[C@@]([2H])(C([2H])([2H])[2H])C(N2[C@]3([H])[C@](CCC3)([H])C[C@H]2C(O)=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.