Fig. 1 · Structure
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Ran-IN-1
Ran GTPase Inhibitor
Ran-IN-1 is a selective inhibitor of Ran GTPase, targeting its role in cellular regulation. It induces cytotoxicity and apoptosis specifically in aneuploid ovarian cancer cells while also inhibiting DNA repair mechanisms. Due to its antitumor activities, Ran-IN-1 is particularly valuable for research applications focused on epithelial ovarian cancer and exploring novel cancer therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2301869-11-2 |
| Applications | Ran GTPase Inhibitor |
| Formula | C27H26F3NO4S |
| Molecular Weight | 517.56 |
| SMILES | FC1=CC=C(COC[C@@H]2[C@@H](OCC3=CC=C(F)C=C3)[C@@H](OCC4=CC=C(F)C=C4)[C@H](C(N)=S)O2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.