Fig. 1 · Structure
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Ranimustine
Alkylating Agent
Ranimustine is a nitrosourea alkylating agent that functions by cross-linking DNA, thereby disrupting DNA replication and transcription. Its primary biological activity relates to its cytotoxic effects on rapidly dividing cells, making it a valuable tool in the study of chronic myelogenous leukemia and polycythemia vera. Ranimustine is utilized in research designed to explore mechanisms of resistance and therapeutic efficacy in hematological malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 58994-96-0 |
| Applications | Alkylating Agent |
| Formula | C10H18ClN3O7 |
| Molecular Weight | 327.72 |
| Synonyms | MCNU |
| SMILES | O[C@H]1[C@@H](OC)O[C@H](CNC(N(CCCl)N=O)=O)[C@@H](O)[C@@H]1O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.