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Ranitidine-d6

Stable Isotope

Ranitidine-d6 is a deuterium-labeled form of Ranitidine, a selective and orally active antagonist of the histamine H2-receptor, primarily involved in the inhibition of gastric acid secretion. This compound effectively antagonizes histamine-induced cardiovascular responses in isolated guinea pig atria and modulates uterine activity in rat models, showcasing pA2 values of 7.2 and 6.95, respectively. Additionally, Ranitidine has demonstrated potential in inhibiting breast tumor progression in murine studies, making it valuable for pharmacological research and cancer biology applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1185514-83-3
Applications	Stable Isotope
Formula	C₁₃H₁₆D₆N₄O₃S
Molecular Weight	320.44
SMILES	CN/C(NCCSCC1=CC=C(CN(C([2H])([2H])[2H])C([2H])([2H])[2H])O1)=C/[N+]([O-])=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.