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RANK-derived TRAF6 inhibitor

TRAF6 Inhibitor

RANK-derived TRAF6 inhibitor is a peptide that specifically inhibits TRAF6, disrupting its interaction with LMP1 with an IC50 of 177 nM. This compound has been shown to significantly reduce cell viability in LMP1-dependent lymphoblastoid cell lines (LCLs). It serves as a valuable tool for investigating the role of TRAF6 in signaling pathways and exploring potential therapeutic interventions in related diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1393741-66-6
Applications	TRAF6 Inhibitor
Formula	C₁₅₈H₂₅₀N₄₈O₄₀S
Molecular Weight	3494.04
SMILES	C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N4[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC5=CC=C(O)C=C5)C(O)=O)=O)CCC(O)=O)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)CCC4)[C@H](CC)C)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)=O)CCCCN)=O)CCSC)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)CC(N)=O)=O)CCC(N)=O)=O)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)[C@H](CC)C)=O)CCCCN)=O)[C@H](CC)C)=O)C=6C=7C(NC6)=CC=CC7

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.