Fig. 1 · Structure
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Ranosidenib
Cat. No.
A75792
CAS
2301974-60-5
Isocitrate Dehydrogenase Inhibitor
Ranosidenib is an isocitrate dehydrogenase (IDH) inhibitor that exhibits significant antitumor activity. By targeting the IDH enzyme, it disrupts metabolic pathways critical for cancer cell proliferation. This compound is primarily utilized in research applications focused on cancer metabolism and therapeutic strategies for IDH-mutant tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2301974-60-5 |
| Applications | Isocitrate Dehydrogenase Inhibitor |
| Formula | C15H16F9N5O |
| Molecular Weight | 453.31 |
| SMILES | FC1=C(CCC(F)([C@H]1O)F)C2=NC(N[C@H](C)C(F)(F)F)=NC(N[C@H](C)C(F)(F)F)=N2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.