Ras-IN-3144

Catalog No.: A17222

pan-RAS inhibitor

Ras-IN-3144

Ras-IN-3144 Chemical Structure

CAS NO. 1835283-94-7

Ras-IN-3144 is a pan-RAS inhibitor which inhibits RAS signaling pathways in cancer cells and prevents the growth of RAS mutant mouse cancer xenografts.

Availability: In stock

Package Price Qty
1 mg
$160.00
5 mg
$400.00
10 mg
$680.00
50 mg
$2,200.00
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Biological Activity

Ras-IN-3144 is a pan-RAS inhibitor which inhibits RAS signaling pathways in cancer cells and prevents the growth of RAS mutant mouse cancer xenografts.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 13.96 mL 69.81 mL 139.61 mL
0.5 mM 2.79 mL 13.96 mL 27.92 mL
1 mM 1.4 mL 6.98 mL 13.96 mL
5 mM 0.28 mL 1.4 mL 2.79 mL

*The above data is based on the productmolecular weight 716.262. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17222
Actions Inhibitor
CAS No. 1835283-94-7
Formula C36H41Cl2F3N6O2
M. Wt 716.262
Solubility DMSO
Purity >98%
Synonyms RasIN3144, Ras IN-3144; Ras-IN 3144; Ras-IN-3144; 3144; pan-RAS inhibitor-3144
SMILES O=C(C1(N)CCNCC1)NCCCN2C=C(C3=CC=C(OC(F)(F)F)C=C3)C4=C2C=CC(CN5CCN(CC6=C(Cl)C=CC=C6Cl)CC5)=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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